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Inference of Structure Ensembles of Flexible Biomolecules from Sparse, Averaged Data
We present the theoretical foundations of a general principle to infer structure ensembles of flexible biomolecules from spatially and temporally averaged data obtained in biophysical experiments. The central idea is to compute the Kullback-Leibler optimal modification of a given prior distribution...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820694/ https://www.ncbi.nlm.nih.gov/pubmed/24244505 http://dx.doi.org/10.1371/journal.pone.0079439 |