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AcSDKP Regulates Cell Proliferation through the PI3KCA/Akt Signaling Pathway
The natural tetrapeptide acetyl-N-Ser-Asp-Lys-Pro (AcSDKP) is generated from the N-terminus of thymosin-β4 through enzymatic cleavage by prolyl oligopeptidase (POP). AcSDKP regulation of proliferation of different cells is implicated in hematopoiesis and angiogenesis. This tetrapeptide present in al...
Autores principales: | Hu, Ping, Li, Bin, Zhang, Wenhua, Li, Yijian, Li, Guang, Jiang, Xinnong, Wdzieczak-Bakala, Joanna, Liu, Jianmiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820705/ https://www.ncbi.nlm.nih.gov/pubmed/24244481 http://dx.doi.org/10.1371/journal.pone.0079321 |
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