The Inflammatory Kinase MAP4K4 Promotes Reactivation of Kaposi's Sarcoma Herpesvirus and Enhances the Invasiveness of Infected Endothelial Cells

Kaposi's sarcoma (KS) is a mesenchymal tumour, which is caused by Kaposi's sarcoma herpesvirus (KSHV) and develops under inflammatory conditions. KSHV-infected endothelial spindle cells, the neoplastic cells in KS, show increased invasiveness, attributed to the elevated expression of metal...

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Detalles Bibliográficos
Autores principales: Haas, Darya A., Bala, Kiran, Büsche, Guntram, Weidner-Glunde, Magdalena, Santag, Susann, Kati, Semra, Gramolelli, Silvia, Damas, Modester, Dittrich-Breiholz, Oliver, Kracht, Michael, Rückert, Jessica, Varga, Zoltan, Keri, György, Schulz, Thomas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820715/
https://www.ncbi.nlm.nih.gov/pubmed/24244164
http://dx.doi.org/10.1371/journal.ppat.1003737

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