Recurrent Tissue-Specific mtDNA Mutations Are Common in Humans

Mitochondrial DNA (mtDNA) variation can affect phenotypic variation; therefore, knowing its distribution within and among individuals is of importance to understanding many human diseases. Intra-individual mtDNA variation (heteroplasmy) has been generally assumed to be random. We used massively para...

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Detalles Bibliográficos
Autores principales: Samuels, David C., Li, Chun, Li, Bingshan, Song, Zhuo, Torstenson, Eric, Boyd Clay, Hayley, Rokas, Antonis, Thornton-Wells, Tricia A., Moore, Jason H., Hughes, Tia M., Hoffman, Robert D., Haines, Jonathan L., Murdock, Deborah G., Mortlock, Douglas P., Williams, Scott M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820769/
https://www.ncbi.nlm.nih.gov/pubmed/24244193
http://dx.doi.org/10.1371/journal.pgen.1003929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820769/
https://www.ncbi.nlm.nih.gov/pubmed/24244193
http://dx.doi.org/10.1371/journal.pgen.1003929

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