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A Genetic Approach to the Recruitment of PRC2 at the HoxD Locus

Polycomb group (PcG) proteins are essential for the repression of key factors during early development. In Drosophila, the polycomb repressive complexes (PRC) associate with defined polycomb response DNA elements (PREs). In mammals, however, the mechanisms underlying polycomb recruitment at targeted...

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Detalles Bibliográficos
Autores principales: Schorderet, Patrick, Lonfat, Nicolas, Darbellay, Fabrice, Tschopp, Patrick, Gitto, Sandra, Soshnikova, Natalia, Duboule, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820793/
https://www.ncbi.nlm.nih.gov/pubmed/24244202
http://dx.doi.org/10.1371/journal.pgen.1003951