RNA∶DNA Hybrids Initiate Quasi-Palindrome-Associated Mutations in Highly Transcribed Yeast DNA

RNase H enzymes promote genetic stability by degrading aberrant RNA∶DNA hybrids and by removing ribonucleotide monophosphates (rNMPs) that are present in duplex DNA. Here, we report that loss of RNase H2 in yeast is associated with mutations that extend identity between the arms of imperfect inverte...

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Detalles Bibliográficos
Autores principales: Kim, Nayun, Cho, Jang-Eun, Li, Yue C., Jinks-Robertson, Sue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820800/
https://www.ncbi.nlm.nih.gov/pubmed/24244191
http://dx.doi.org/10.1371/journal.pgen.1003924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820800/
https://www.ncbi.nlm.nih.gov/pubmed/24244191
http://dx.doi.org/10.1371/journal.pgen.1003924

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