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Activin Signaling Targeted by Insulin/dFOXO Regulates Aging and Muscle Proteostasis in Drosophila

Reduced insulin/IGF signaling increases lifespan in many animals. To understand how insulin/IGF mediates lifespan in Drosophila, we performed chromatin immunoprecipitation-sequencing analysis with the insulin/IGF regulated transcription factor dFOXO in long-lived insulin/IGF signaling genotypes. Daw...

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Detalles Bibliográficos
Autores principales:	Bai, Hua, Kang, Ping, Hernandez, Ana Maria, Tatar, Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820802/ https://www.ncbi.nlm.nih.gov/pubmed/24244197 http://dx.doi.org/10.1371/journal.pgen.1003941

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