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The carboxy-terminal segment of the human LINE-1 ORF2 protein is involved in RNA binding()

The human LINE-1/L1 ORF2 protein is a multifunctional enzyme which plays a vital role in the life cycle of the human L1 retrotransposon. The protein consists of an endonuclease domain, followed by a central reverse transcriptase domain and a carboxy-terminal C-domain with unknown function. Here, we...

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Detalles Bibliográficos
Autores principales: Piskareva, Olga, Ernst, Christina, Higgins, Niamh, Schmatchenko, Vadim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821027/
https://www.ncbi.nlm.nih.gov/pubmed/24251107
http://dx.doi.org/10.1016/j.fob.2013.09.005