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Structural and thermodynamic insight into phenylalanine hydroxylase from the human pathogen Legionella pneumophila()
Phenylalanine hydroxylase from Legionella pneumophila (lpPAH) has a major functional role in the synthesis of the pigment pyomelanin, which is a potential virulence factor. We present here the crystal structure of lpPAH, which is a dimeric enzyme that shows high thermostability, with a midpoint dena...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821034/ https://www.ncbi.nlm.nih.gov/pubmed/24251098 http://dx.doi.org/10.1016/j.fob.2013.08.006 |