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Minimum Appropriate Dose of Lidocaine with a Fixed Dose of Sufentanil Epinephrine Used for Spinal Anesthesia in Caesarian Section

BACKGROUND: Caesarian section is a commonplace surgery in females for which spinal anesthesia is the preferred method. The local anesthetic medications used in the surgery are often associated with complications such as nausea, vomiting, dyspnea, hypotension, and bradycardia. In the present study, w...

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Autores principales: Golfam, Parisa, Yari, Mitra, Bakhtiyari, Hamid Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821131/
https://www.ncbi.nlm.nih.gov/pubmed/24244922
http://dx.doi.org/10.5812/aapm.7810
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author Golfam, Parisa
Yari, Mitra
Bakhtiyari, Hamid Reza
author_facet Golfam, Parisa
Yari, Mitra
Bakhtiyari, Hamid Reza
author_sort Golfam, Parisa
collection PubMed
description BACKGROUND: Caesarian section is a commonplace surgery in females for which spinal anesthesia is the preferred method. The local anesthetic medications used in the surgery are often associated with complications such as nausea, vomiting, dyspnea, hypotension, and bradycardia. In the present study, we decreased the dose of the anesthetic drug and added an opioid instead. OBJECTIVES: We tried to find an appropriate combination of medications required for optimal anesthesia with minimum complications. PATIENTS AND METHODS: One hundred twenty six candidates for C/S with first and second class ASA aged 18-35 years were randomly divided into three groups. All patients received sufentanil (2.5 µg) and epinephrine (100 µg) doses but the lidocaine doses were respectively 50 mg, 60 mg and 75 mg in the groups 1, 2 and 3. Complications including hypotension, bradycardia, dyspnea, nausea, vomiting, and anesthesia quality were recorded and statistically analyzed. RESULTS: The level of anesthesia was significantly different between groups. By reducing the lidocaine dose, patients with anesthesia level under the nipple increased but the surgeon and the patient were satisfied with the results. Nausea, vomiting, and dyspnea was degraded by decreasing the lidocaine dose especially in the 50 mg group. The need to use ephedrine was directly associated with the lidocaine. However, the need to use atropine was not significantly different between groups. Pruritus was not significantly different as well. CONCLUSIONS: It seems that reducing the lidocaine dose, when combined with sufentanil, decreases most complications of spinal anesthesia such as hypotension, dyspnea, nausea, and vomiting while preserving anesthesia quality.
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spelling pubmed-38211312013-11-15 Minimum Appropriate Dose of Lidocaine with a Fixed Dose of Sufentanil Epinephrine Used for Spinal Anesthesia in Caesarian Section Golfam, Parisa Yari, Mitra Bakhtiyari, Hamid Reza Anesth Pain Med Research Article BACKGROUND: Caesarian section is a commonplace surgery in females for which spinal anesthesia is the preferred method. The local anesthetic medications used in the surgery are often associated with complications such as nausea, vomiting, dyspnea, hypotension, and bradycardia. In the present study, we decreased the dose of the anesthetic drug and added an opioid instead. OBJECTIVES: We tried to find an appropriate combination of medications required for optimal anesthesia with minimum complications. PATIENTS AND METHODS: One hundred twenty six candidates for C/S with first and second class ASA aged 18-35 years were randomly divided into three groups. All patients received sufentanil (2.5 µg) and epinephrine (100 µg) doses but the lidocaine doses were respectively 50 mg, 60 mg and 75 mg in the groups 1, 2 and 3. Complications including hypotension, bradycardia, dyspnea, nausea, vomiting, and anesthesia quality were recorded and statistically analyzed. RESULTS: The level of anesthesia was significantly different between groups. By reducing the lidocaine dose, patients with anesthesia level under the nipple increased but the surgeon and the patient were satisfied with the results. Nausea, vomiting, and dyspnea was degraded by decreasing the lidocaine dose especially in the 50 mg group. The need to use ephedrine was directly associated with the lidocaine. However, the need to use atropine was not significantly different between groups. Pruritus was not significantly different as well. CONCLUSIONS: It seems that reducing the lidocaine dose, when combined with sufentanil, decreases most complications of spinal anesthesia such as hypotension, dyspnea, nausea, and vomiting while preserving anesthesia quality. Kowsar 2013-01-01 2013 /pmc/articles/PMC3821131/ /pubmed/24244922 http://dx.doi.org/10.5812/aapm.7810 Text en Copyright © 2013, Iranian Society of Regional Anesthesia and Pain Medicine http://creativecommons.org/licenses/by/3/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Golfam, Parisa
Yari, Mitra
Bakhtiyari, Hamid Reza
Minimum Appropriate Dose of Lidocaine with a Fixed Dose of Sufentanil Epinephrine Used for Spinal Anesthesia in Caesarian Section
title Minimum Appropriate Dose of Lidocaine with a Fixed Dose of Sufentanil Epinephrine Used for Spinal Anesthesia in Caesarian Section
title_full Minimum Appropriate Dose of Lidocaine with a Fixed Dose of Sufentanil Epinephrine Used for Spinal Anesthesia in Caesarian Section
title_fullStr Minimum Appropriate Dose of Lidocaine with a Fixed Dose of Sufentanil Epinephrine Used for Spinal Anesthesia in Caesarian Section
title_full_unstemmed Minimum Appropriate Dose of Lidocaine with a Fixed Dose of Sufentanil Epinephrine Used for Spinal Anesthesia in Caesarian Section
title_short Minimum Appropriate Dose of Lidocaine with a Fixed Dose of Sufentanil Epinephrine Used for Spinal Anesthesia in Caesarian Section
title_sort minimum appropriate dose of lidocaine with a fixed dose of sufentanil epinephrine used for spinal anesthesia in caesarian section
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821131/
https://www.ncbi.nlm.nih.gov/pubmed/24244922
http://dx.doi.org/10.5812/aapm.7810
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