Central Nervous System Toxicity After Botulinum Neurotoxin Injection

Since Its first description of botulism toxicity in 1820s, specific formulations of botulinum neurotoxin (BoNT) have been introduced with different clinical benefits. However, there is increasing number of adverse events reported to Food and Drug Administration. This report presents the case of 62-y...

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Autores principales: Ilkhchoui, Yashar, Ghaly, Ramsis F., Knezevic, N. Nick, Candido, Kenneth D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821148/
https://www.ncbi.nlm.nih.gov/pubmed/24223367
http://dx.doi.org/10.5812/aapm.9356
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author Ilkhchoui, Yashar
Ghaly, Ramsis F.
Knezevic, N. Nick
Candido, Kenneth D
author_facet Ilkhchoui, Yashar
Ghaly, Ramsis F.
Knezevic, N. Nick
Candido, Kenneth D
author_sort Ilkhchoui, Yashar
collection PubMed
description Since Its first description of botulism toxicity in 1820s, specific formulations of botulinum neurotoxin (BoNT) have been introduced with different clinical benefits. However, there is increasing number of adverse events reported to Food and Drug Administration. This report presents the case of 62-year-old woman with Parkinson’s disease who received BoNT injections to treat painful spasticity in her hands. She developed severe generalized dystonia shortly after BoNT injections.
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spelling pubmed-38211482013-11-12 Central Nervous System Toxicity After Botulinum Neurotoxin Injection Ilkhchoui, Yashar Ghaly, Ramsis F. Knezevic, N. Nick Candido, Kenneth D Anesth Pain Med Case Report Since Its first description of botulism toxicity in 1820s, specific formulations of botulinum neurotoxin (BoNT) have been introduced with different clinical benefits. However, there is increasing number of adverse events reported to Food and Drug Administration. This report presents the case of 62-year-old woman with Parkinson’s disease who received BoNT injections to treat painful spasticity in her hands. She developed severe generalized dystonia shortly after BoNT injections. Kowsar 2013-07-01 2013 /pmc/articles/PMC3821148/ /pubmed/24223367 http://dx.doi.org/10.5812/aapm.9356 Text en Copyright © 2013, Iranian Society of Regional Anesthesia and Pain Medicine (ISRAPM) http://creativecommons.org/licenses/by/3/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ilkhchoui, Yashar
Ghaly, Ramsis F.
Knezevic, N. Nick
Candido, Kenneth D
Central Nervous System Toxicity After Botulinum Neurotoxin Injection
title Central Nervous System Toxicity After Botulinum Neurotoxin Injection
title_full Central Nervous System Toxicity After Botulinum Neurotoxin Injection
title_fullStr Central Nervous System Toxicity After Botulinum Neurotoxin Injection
title_full_unstemmed Central Nervous System Toxicity After Botulinum Neurotoxin Injection
title_short Central Nervous System Toxicity After Botulinum Neurotoxin Injection
title_sort central nervous system toxicity after botulinum neurotoxin injection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821148/
https://www.ncbi.nlm.nih.gov/pubmed/24223367
http://dx.doi.org/10.5812/aapm.9356
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