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Endovascular treatment of acute ischemic stroke

Early recanalization of the occluded artery leads to better clinical outcomes in patients with acute ischemic stroke (AIS) through protection of the time-sensitive penumbra. Intravenous administration of pharmacologic thrombolytic agents has been a standard treatment for AIS. To get better rates of...

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Autores principales: Singh, Paramdeep, Kaur, Rupinderjeet, Kaur, Amarpreet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821416/
https://www.ncbi.nlm.nih.gov/pubmed/24250163
http://dx.doi.org/10.4103/0976-3147.118787
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author Singh, Paramdeep
Kaur, Rupinderjeet
Kaur, Amarpreet
author_facet Singh, Paramdeep
Kaur, Rupinderjeet
Kaur, Amarpreet
author_sort Singh, Paramdeep
collection PubMed
description Early recanalization of the occluded artery leads to better clinical outcomes in patients with acute ischemic stroke (AIS) through protection of the time-sensitive penumbra. Intravenous administration of pharmacologic thrombolytic agents has been a standard treatment for AIS. To get better rates of recanalization, enhance the time window, and diminish the possibility of intracranial hemorrhage, endovascular thrombectomy was launched, with first authorization of the Merci clot retriever, a corkscrew-like apparatus, followed by approval of the Penumbra thromboaspiration system. Both devices lead to a high rate of recanalization. On the other hand, time to recanalization was on an average of 45 minutes, with most of the patients attaining only partial recanalization. More lately, retrievable stents have shown promise in decreasing the time to recanalization, and attaining a superior rate of complete clot resolution. The retrievable stent can be released within the clot to engage it within the struts of the stent, and afterwards it is taken back by pulling it under flow arrest. Neurointerventional techniques have a persistently ever-increasing and stimulating role in the management of AIS, as indicated by the advent of several important techniques. Stent retrievers have the capability to be ascertained as the most important approach to endovascular stroke treatment.
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spelling pubmed-38214162013-11-18 Endovascular treatment of acute ischemic stroke Singh, Paramdeep Kaur, Rupinderjeet Kaur, Amarpreet J Neurosci Rural Pract Review Article Early recanalization of the occluded artery leads to better clinical outcomes in patients with acute ischemic stroke (AIS) through protection of the time-sensitive penumbra. Intravenous administration of pharmacologic thrombolytic agents has been a standard treatment for AIS. To get better rates of recanalization, enhance the time window, and diminish the possibility of intracranial hemorrhage, endovascular thrombectomy was launched, with first authorization of the Merci clot retriever, a corkscrew-like apparatus, followed by approval of the Penumbra thromboaspiration system. Both devices lead to a high rate of recanalization. On the other hand, time to recanalization was on an average of 45 minutes, with most of the patients attaining only partial recanalization. More lately, retrievable stents have shown promise in decreasing the time to recanalization, and attaining a superior rate of complete clot resolution. The retrievable stent can be released within the clot to engage it within the struts of the stent, and afterwards it is taken back by pulling it under flow arrest. Neurointerventional techniques have a persistently ever-increasing and stimulating role in the management of AIS, as indicated by the advent of several important techniques. Stent retrievers have the capability to be ascertained as the most important approach to endovascular stroke treatment. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3821416/ /pubmed/24250163 http://dx.doi.org/10.4103/0976-3147.118787 Text en Copyright: © Journal of Neurosciences in Rural Practice http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Singh, Paramdeep
Kaur, Rupinderjeet
Kaur, Amarpreet
Endovascular treatment of acute ischemic stroke
title Endovascular treatment of acute ischemic stroke
title_full Endovascular treatment of acute ischemic stroke
title_fullStr Endovascular treatment of acute ischemic stroke
title_full_unstemmed Endovascular treatment of acute ischemic stroke
title_short Endovascular treatment of acute ischemic stroke
title_sort endovascular treatment of acute ischemic stroke
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821416/
https://www.ncbi.nlm.nih.gov/pubmed/24250163
http://dx.doi.org/10.4103/0976-3147.118787
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