The effect of covariate adjustment for baseline severity in acute stroke clinical trials with responder analysis outcomes

BACKGROUND: Traditionally in acute stroke clinical trials, the primary clinical outcome employed is a dichotomized modified Rankin Scale (mRS). New statistical methods, such as responder analysis, are being used in stroke studies to address the concern that baseline prognostic variables, such as str...

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Detalles Bibliográficos
Autores principales: Garofolo, Kyra M, Yeatts, Sharon D, Ramakrishnan, Viswanathan, Jauch, Edward C, Johnston, Karen C, Durkalski, Valerie L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821551/
https://www.ncbi.nlm.nih.gov/pubmed/24499406
http://dx.doi.org/10.1186/1745-6215-14-98

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