Synthesis and Activity of Novel Acylthiourea with Hydantoin

The 41 novel acylthiourea derivatives with hydantoin were synthesized in moderate to excellent yields by using 5-(4-aminophenyl)- and 5-(4-aminobenzyl)- hydantoin or 5-(4-aminobenzyl)-thiohydantoin as raw materials and characterized by IR, (1)H NMR spectra and elementary analysis. The preliminary bi...

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Detalles Bibliográficos
Autores principales: Han, Jintao, Dong, Hongbo, Xu, Zhihong, Wang, Jinmin, Wang, Mingan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821571/
https://www.ncbi.nlm.nih.gov/pubmed/24077124
http://dx.doi.org/10.3390/ijms141019526
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author Han, Jintao
Dong, Hongbo
Xu, Zhihong
Wang, Jinmin
Wang, Mingan
author_facet Han, Jintao
Dong, Hongbo
Xu, Zhihong
Wang, Jinmin
Wang, Mingan
author_sort Han, Jintao
collection PubMed
description The 41 novel acylthiourea derivatives with hydantoin were synthesized in moderate to excellent yields by using 5-(4-aminophenyl)- and 5-(4-aminobenzyl)- hydantoin or 5-(4-aminobenzyl)-thiohydantoin as raw materials and characterized by IR, (1)H NMR spectra and elementary analysis. The preliminary bioassay showed that these compounds exhibit certain selectively herbicidal activities with the 91%, 94% and 87% inhibition rates of 7l, 8o and 8p against B. campestris, 100%, 100% and 95% efficacy against B. campestris in a greenhouse test, respectively. 7a, 7b, 7c and 7d exhibited 74%, 79%, 79% and 71% inhibition rates against F. oxysporum, respectively.
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spelling pubmed-38215712013-11-11 Synthesis and Activity of Novel Acylthiourea with Hydantoin Han, Jintao Dong, Hongbo Xu, Zhihong Wang, Jinmin Wang, Mingan Int J Mol Sci Article The 41 novel acylthiourea derivatives with hydantoin were synthesized in moderate to excellent yields by using 5-(4-aminophenyl)- and 5-(4-aminobenzyl)- hydantoin or 5-(4-aminobenzyl)-thiohydantoin as raw materials and characterized by IR, (1)H NMR spectra and elementary analysis. The preliminary bioassay showed that these compounds exhibit certain selectively herbicidal activities with the 91%, 94% and 87% inhibition rates of 7l, 8o and 8p against B. campestris, 100%, 100% and 95% efficacy against B. campestris in a greenhouse test, respectively. 7a, 7b, 7c and 7d exhibited 74%, 79%, 79% and 71% inhibition rates against F. oxysporum, respectively. Molecular Diversity Preservation International (MDPI) 2013-09-26 /pmc/articles/PMC3821571/ /pubmed/24077124 http://dx.doi.org/10.3390/ijms141019526 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Han, Jintao
Dong, Hongbo
Xu, Zhihong
Wang, Jinmin
Wang, Mingan
Synthesis and Activity of Novel Acylthiourea with Hydantoin
title Synthesis and Activity of Novel Acylthiourea with Hydantoin
title_full Synthesis and Activity of Novel Acylthiourea with Hydantoin
title_fullStr Synthesis and Activity of Novel Acylthiourea with Hydantoin
title_full_unstemmed Synthesis and Activity of Novel Acylthiourea with Hydantoin
title_short Synthesis and Activity of Novel Acylthiourea with Hydantoin
title_sort synthesis and activity of novel acylthiourea with hydantoin
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821571/
https://www.ncbi.nlm.nih.gov/pubmed/24077124
http://dx.doi.org/10.3390/ijms141019526
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AT wangjinmin synthesisandactivityofnovelacylthioureawithhydantoin
AT wangmingan synthesisandactivityofnovelacylthioureawithhydantoin

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