A Computational Drug Metabolite Detection Using the Stable Isotopic Mass-Shift Filtering with High Resolution Mass Spectrometry in Pioglitazone and Flurbiprofen

The identification of metabolites in drug discovery is important. At present, radioisotopes and mass spectrometry are both widely used. However, rapid and comprehensive identification is still laborious and difficult. In this study, we developed new analytical software and employed a stable isotope...

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Detalles Bibliográficos
Autores principales: Uchida, Masashi, Kanazawa, Mitsuhiro, Ogiwara, Atsushi, Sezaki, Hiroshi, Ando, Akihiro, Miyamoto, Yohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Technical Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821582/
https://www.ncbi.nlm.nih.gov/pubmed/24084721
http://dx.doi.org/10.3390/ijms141019716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821582/
https://www.ncbi.nlm.nih.gov/pubmed/24084721
http://dx.doi.org/10.3390/ijms141019716

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