Identification of Combined Genetic Determinants of Liver Stiffness within the SREBP1c-PNPLA3 Pathway

The common PNPLA3 (adiponutrin) variant, p.I148M, was identified as a genetic determinant of liver fibrosis. Since the expression of PNPLA3 is induced by sterol regulatory element binding protein 1c (SREBP1c), we investigate two common SREBP1c variants (rs2297508 and rs11868035) for their associatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Krawczyk, Marcin, Grünhage, Frank, Lammert, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821663/
https://www.ncbi.nlm.nih.gov/pubmed/24152445
http://dx.doi.org/10.3390/ijms141021153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821663/
https://www.ncbi.nlm.nih.gov/pubmed/24152445
http://dx.doi.org/10.3390/ijms141021153

Ejemplares similares