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Role of the Acidic Tail of High Mobility Group Protein B1 (HMGB1) in Protein Stability and DNA Bending

High mobility group box (HMGB) proteins are abundant nonhistone proteins found in all eukaryotic nuclei and are capable of binding/bending DNA. The human HMGB1 is composed of two binding motifs, known as Boxes A and B, are L-shaped alpha-helix structures, followed by a random-coil acidic tail that c...

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Detalles Bibliográficos
Autores principales:	Belgrano, Fabricio S., de Abreu da Silva, Isabel C., Bastos de Oliveira, Francisco M., Fantappié, Marcelo R., Mohana-Borges, Ronaldo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821859/ https://www.ncbi.nlm.nih.gov/pubmed/24255708 http://dx.doi.org/10.1371/journal.pone.0079572

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