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Charting a dynamic DNA methylation landscape of the human genome

DNA methylation is a defining feature of mammalian cellular identity and essential for normal development(1,2). Most cell types, except germ cells and pre-implantation embryos(3–5), display relatively stable DNA methylation patterns with 70–80% of all CpGs being methylated(6). Despite recent advance...

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Detalles Bibliográficos
Autores principales: Ziller, Michael J., Gu, Hongcang, Müller, Fabian, Donaghey, Julie, Tsai, Linus T.-Y., Kohlbacher, Oliver, De Jager, Phil L., Rosen, Evan D., Bennett, David A., Bernstein, Bradley E., Gnirke, Andreas, Meissner, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821869/
https://www.ncbi.nlm.nih.gov/pubmed/23925113
http://dx.doi.org/10.1038/nature12433