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Charting a dynamic DNA methylation landscape of the human genome
DNA methylation is a defining feature of mammalian cellular identity and essential for normal development(1,2). Most cell types, except germ cells and pre-implantation embryos(3–5), display relatively stable DNA methylation patterns with 70–80% of all CpGs being methylated(6). Despite recent advance...
Autores principales: | Ziller, Michael J., Gu, Hongcang, Müller, Fabian, Donaghey, Julie, Tsai, Linus T.-Y., Kohlbacher, Oliver, De Jager, Phil L., Rosen, Evan D., Bennett, David A., Bernstein, Bradley E., Gnirke, Andreas, Meissner, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821869/ https://www.ncbi.nlm.nih.gov/pubmed/23925113 http://dx.doi.org/10.1038/nature12433 |
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