A discovery study of daunorubicin induced cardiotoxicity in a sample of acute myeloid leukemia patients prioritizes P450 oxidoreductase polymorphisms as a potential risk factor

Anthracyclines are very effective chemotherapeutic agents; however, their use is hampered by the treatment-induced cardiotoxicity. Genetic variants that help define patient's sensitivity to anthracyclines will greatly improve the design of optimal chemotherapeutic regimens. However, identificat...

Descripción completa

Detalles Bibliográficos
Autores principales: Lubieniecka, Joanna M., Graham, Jinko, Heffner, Daniel, Mottus, Randy, Reid, Ronald, Hogge, Donna, Grigliatti, Tom A., Riggs, Wayne K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822292/
https://www.ncbi.nlm.nih.gov/pubmed/24273552
http://dx.doi.org/10.3389/fgene.2013.00231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822292/
https://www.ncbi.nlm.nih.gov/pubmed/24273552
http://dx.doi.org/10.3389/fgene.2013.00231

Ejemplares similares