Dendritic Cell Derived Cytokines in Human Natural Killer Cell Differentiation and Activation

Dendritic cells (DCs) and natural killer (NK) cells shape each other’s functions early during immune responses. DCs activate NK cells and NK cells can mature or kill DCs. In this review we will discuss which DC and NK cell subsets are mainly affected by this interaction, where these encounters might...

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Autores principales: Chijioke, Obinna, Münz, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822368/
https://www.ncbi.nlm.nih.gov/pubmed/24273539
http://dx.doi.org/10.3389/fimmu.2013.00365
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author Chijioke, Obinna
Münz, Christian
author_facet Chijioke, Obinna
Münz, Christian
author_sort Chijioke, Obinna
collection PubMed
description Dendritic cells (DCs) and natural killer (NK) cells shape each other’s functions early during immune responses. DCs activate NK cells and NK cells can mature or kill DCs. In this review we will discuss which DC and NK cell subsets are mainly affected by this interaction, where these encounters might take place and which signals are exchanged. Finally, we will point out what the clinical benefit of understanding this interaction might be and how it changed our view on NK cells as innate lymphocytes.
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spelling pubmed-38223682013-11-22 Dendritic Cell Derived Cytokines in Human Natural Killer Cell Differentiation and Activation Chijioke, Obinna Münz, Christian Front Immunol Immunology Dendritic cells (DCs) and natural killer (NK) cells shape each other’s functions early during immune responses. DCs activate NK cells and NK cells can mature or kill DCs. In this review we will discuss which DC and NK cell subsets are mainly affected by this interaction, where these encounters might take place and which signals are exchanged. Finally, we will point out what the clinical benefit of understanding this interaction might be and how it changed our view on NK cells as innate lymphocytes. Frontiers Media S.A. 2013-11-11 /pmc/articles/PMC3822368/ /pubmed/24273539 http://dx.doi.org/10.3389/fimmu.2013.00365 Text en Copyright © 2013 Chijioke and Münz. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Chijioke, Obinna
Münz, Christian
Dendritic Cell Derived Cytokines in Human Natural Killer Cell Differentiation and Activation
title Dendritic Cell Derived Cytokines in Human Natural Killer Cell Differentiation and Activation
title_full Dendritic Cell Derived Cytokines in Human Natural Killer Cell Differentiation and Activation
title_fullStr Dendritic Cell Derived Cytokines in Human Natural Killer Cell Differentiation and Activation
title_full_unstemmed Dendritic Cell Derived Cytokines in Human Natural Killer Cell Differentiation and Activation
title_short Dendritic Cell Derived Cytokines in Human Natural Killer Cell Differentiation and Activation
title_sort dendritic cell derived cytokines in human natural killer cell differentiation and activation
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822368/
https://www.ncbi.nlm.nih.gov/pubmed/24273539
http://dx.doi.org/10.3389/fimmu.2013.00365
work_keys_str_mv AT chijiokeobinna dendriticcellderivedcytokinesinhumannaturalkillercelldifferentiationandactivation
AT munzchristian dendriticcellderivedcytokinesinhumannaturalkillercelldifferentiationandactivation

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