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Analyses of Interactions Between Heparin and the Apical Surface Proteins of Plasmodium falciparum

Heparin, a sulfated glycoconjugate, reportedly inhibits the blood-stage growth of the malaria parasite Plasmodium falciparum. Elucidation of the inhibitory mechanism is valuable for developing novel invasion-blocking treatments based on heparin. Merozoite surface protein 1 has been reported as a can...

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Detalles Bibliográficos
Autores principales: Kobayashi, Kyousuke, Takano, Ryo, Takemae, Hitoshi, Sugi, Tatsuki, Ishiwa, Akiko, Gong, Haiyan, Recuenco, Frances C., Iwanaga, Tatsuya, Horimoto, Taisuke, Akashi, Hiroomi, Kato, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822384/
https://www.ncbi.nlm.nih.gov/pubmed/24212193
http://dx.doi.org/10.1038/srep03178