Cargando…

Abnormal extraosseous activity in both lungs and stomach in pre-transplant 99mTc-MDP bone scan disappearing after renal transplant

A chronic kidney disease male patient presenting with bone pains, fever, weakness, and clinically ascites was subjected to four technetium-99m-methylene diphosphonate (Tc99m-MDP) bone scans, two before renal transplant and two after renal transplants. Pretransplant bone scan revealed metabolic bone...

Descripción completa

Detalles Bibliográficos
Autores principales: Sonavane, Sunita Tarsarya, Marwah, Atul, Shah, Hardik, Jaiswar, Rajnath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822416/
https://www.ncbi.nlm.nih.gov/pubmed/24250025
http://dx.doi.org/10.4103/0972-3919.119549
_version_ 1782290410518872064
author Sonavane, Sunita Tarsarya
Marwah, Atul
Shah, Hardik
Jaiswar, Rajnath
author_facet Sonavane, Sunita Tarsarya
Marwah, Atul
Shah, Hardik
Jaiswar, Rajnath
author_sort Sonavane, Sunita Tarsarya
collection PubMed
description A chronic kidney disease male patient presenting with bone pains, fever, weakness, and clinically ascites was subjected to four technetium-99m-methylene diphosphonate (Tc99m-MDP) bone scans, two before renal transplant and two after renal transplants. Pretransplant bone scan revealed metabolic bone disease with focal insufficiency fractures. Marked extraosseous activity in both lungs and stomach was also visualized. On regular hemodialysis (HD) after 4 months, repeat pretransplant bone scan showed persistent uptake in lungs and stomach, representing altered calcium metabolism with microcalcifications. He underwent human leukocyte antigen (HLA) matched live donor renal transplantation, started on immune-suppression and steroids. Posttransplant bone scan at 20 days revealed no definite interval change, but bone scan performed approximately 17 months posttransplant showed resolving metabolic bone disease and the tracer uptake in the lungs and stomach was no more visualized. Patient clinically followed-up until the date (February 2013) is asymptomatic with serum creatinine of 1.5 mg/dl, no bone scan done.
format Online
Article
Text
id pubmed-3822416
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-38224162013-11-18 Abnormal extraosseous activity in both lungs and stomach in pre-transplant 99mTc-MDP bone scan disappearing after renal transplant Sonavane, Sunita Tarsarya Marwah, Atul Shah, Hardik Jaiswar, Rajnath Indian J Nucl Med Case Report A chronic kidney disease male patient presenting with bone pains, fever, weakness, and clinically ascites was subjected to four technetium-99m-methylene diphosphonate (Tc99m-MDP) bone scans, two before renal transplant and two after renal transplants. Pretransplant bone scan revealed metabolic bone disease with focal insufficiency fractures. Marked extraosseous activity in both lungs and stomach was also visualized. On regular hemodialysis (HD) after 4 months, repeat pretransplant bone scan showed persistent uptake in lungs and stomach, representing altered calcium metabolism with microcalcifications. He underwent human leukocyte antigen (HLA) matched live donor renal transplantation, started on immune-suppression and steroids. Posttransplant bone scan at 20 days revealed no definite interval change, but bone scan performed approximately 17 months posttransplant showed resolving metabolic bone disease and the tracer uptake in the lungs and stomach was no more visualized. Patient clinically followed-up until the date (February 2013) is asymptomatic with serum creatinine of 1.5 mg/dl, no bone scan done. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3822416/ /pubmed/24250025 http://dx.doi.org/10.4103/0972-3919.119549 Text en Copyright: © Indian Journal of Nuclear Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Sonavane, Sunita Tarsarya
Marwah, Atul
Shah, Hardik
Jaiswar, Rajnath
Abnormal extraosseous activity in both lungs and stomach in pre-transplant 99mTc-MDP bone scan disappearing after renal transplant
title Abnormal extraosseous activity in both lungs and stomach in pre-transplant 99mTc-MDP bone scan disappearing after renal transplant
title_full Abnormal extraosseous activity in both lungs and stomach in pre-transplant 99mTc-MDP bone scan disappearing after renal transplant
title_fullStr Abnormal extraosseous activity in both lungs and stomach in pre-transplant 99mTc-MDP bone scan disappearing after renal transplant
title_full_unstemmed Abnormal extraosseous activity in both lungs and stomach in pre-transplant 99mTc-MDP bone scan disappearing after renal transplant
title_short Abnormal extraosseous activity in both lungs and stomach in pre-transplant 99mTc-MDP bone scan disappearing after renal transplant
title_sort abnormal extraosseous activity in both lungs and stomach in pre-transplant 99mtc-mdp bone scan disappearing after renal transplant
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822416/
https://www.ncbi.nlm.nih.gov/pubmed/24250025
http://dx.doi.org/10.4103/0972-3919.119549
work_keys_str_mv AT sonavanesunitatarsarya abnormalextraosseousactivityinbothlungsandstomachinpretransplant99mtcmdpbonescandisappearingafterrenaltransplant
AT marwahatul abnormalextraosseousactivityinbothlungsandstomachinpretransplant99mtcmdpbonescandisappearingafterrenaltransplant
AT shahhardik abnormalextraosseousactivityinbothlungsandstomachinpretransplant99mtcmdpbonescandisappearingafterrenaltransplant
AT jaiswarrajnath abnormalextraosseousactivityinbothlungsandstomachinpretransplant99mtcmdpbonescandisappearingafterrenaltransplant