Cargando…
Metformin attenuates ovarian cancer cell growth in an AMP-kinase dispensable manner
Metformin, the most widely used drug for type 2 diabetes activates 59 adenosine monophosphate (AMP)-activated protein kinase (AMPK), which regulates cellular energy metabolism. Here, we report that ovarian cell lines VOSE, A2780, CP70, C200, OV202, OVCAR3, SKOV3ip, PE01 and PE04 predominantly expres...
Autores principales: | Rattan, R, Giri, S, Hartmann, LC, Shridhar, V |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822503/ https://www.ncbi.nlm.nih.gov/pubmed/19874425 http://dx.doi.org/10.1111/j.1582-4934.2009.00954.x |
Ejemplares similares
-
Metformin limits the adipocyte tumor-promoting effect on ovarian cancer
por: Tebbe, Calvin, et al.
Publicado: (2014) -
Metformin prevents aggressive ovarian cancer growth driven by high-energy diet: similarity with calorie restriction
por: Al-Wahab, Zaid, et al.
Publicado: (2015) -
Preclinical Therapeutic Potential of a Nitrosylating Agent in the Treatment of Ovarian Cancer
por: Giri, Shailendra, et al.
Publicado: (2014) -
Elevated basal AMP-activated protein kinase activity sensitizes colorectal cancer cells to growth inhibition by metformin
por: Morrison, Kaitlin R., et al.
Publicado: (2023) -
Metformin attenuates motility, contraction, and fibrogenic response of hepatic stellate cells in vivo and in vitro by activating AMP-activated protein kinase
por: Li, Zhen, et al.
Publicado: (2018)