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Polymorphisms in p53 and the p53 pathway: roles in cancer susceptibility and response to treatment

The p53 tumour suppressor protein lies at the crossroads of multiple cellular response pathways that control the fate of the cell in response to endogenous or exogenous stresses and inactivation of the p53 tumour suppressor signalling pathway is seen in most human cancers. Such aberrant p53 activity...

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Detalles Bibliográficos
Autores principales:	Hrstka, Roman, Coates, Philip J, Vojtesek, Borivoj
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2009
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822507/ https://www.ncbi.nlm.nih.gov/pubmed/19379143 http://dx.doi.org/10.1111/j.1582-4934.2008.00634.x

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