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RXRA gene variations influence Alzheimer's disease risk and cholesterol metabolism

Cholesterol metabolism is altered in Alzheimer's disease (AD). The nuclear hormone receptor Retinoic X Receptor a (RXRa) is a member of the nuclear ligand-activated transcription factor family. RXRs are key regulators of cholesterol synthesis and thus cholesterol metabolism. We performed a syst...

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Detalles Bibliográficos
Autores principales:	Kölsch, Heike, Lütjohann, Dieter, Jessen, Frank, Popp, Julius, Hentschel, Frank, Kelemen, Peter, Friedrichs, Silvia, Maier, TA Wolfgang, Heun, Reinhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2009
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822518/ https://www.ncbi.nlm.nih.gov/pubmed/19374686 http://dx.doi.org/10.1111/j.1582-4934.2009.00383.x

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