Cargando…
Cytokine-induced β-cell apoptosis is NO-dependent, mitochondria-mediated and inhibited by BCL-X(L)
Pro-inflammatory cytokines are implicated as the main mediators of β-cell death during type 1 diabetes but the exact mechanisms remain unknown. This study examined the effects of interleukin-1β (IL-1β), interferon-γ (IFNγ) and tumour necrosis factor α (TNFα) on a rat insulinoma cell line (RIN-r) in...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2008
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822546/ https://www.ncbi.nlm.nih.gov/pubmed/18081694 http://dx.doi.org/10.1111/j.1582-4934.2007.00191.x |