Microparticles – messengers of biological information

Endothelial cell apoptosis is a pivotal step in the development of atherosclerotic disease. Regeneration of the damaged endothelium is an attractive therapy option in the prevention and treatment of atherosclerotic disease. Apoptosis is associated with the release of microparticles (MP). Besides the...

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Detalles Bibliográficos
Autores principales: Hoyer, Friedrich Felix, Nickenig, Georg, Werner, Nikos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822564/
https://www.ncbi.nlm.nih.gov/pubmed/20597998
http://dx.doi.org/10.1111/j.1582-4934.2010.01114.x
Descripción
Sumario:Endothelial cell apoptosis is a pivotal step in the development of atherosclerotic disease. Regeneration of the damaged endothelium is an attractive therapy option in the prevention and treatment of atherosclerotic disease. Apoptosis is associated with the release of microparticles (MP). Besides their role as marker of cell damage, recent reports have underlined their role as signalling elements in cell–cell communication. In this review, we focus on the emerging role of circulating MP as transmitters of biological information in cardiovascular disease.

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