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Growth inhibition of colorectal carcinoma by lentiviral TRAIL-transgenic human mesenchymal stem cells requires their substantial intratumoral presence
Colorectal carcinoma (CRC) constitutes a common malignancy with limited therapeutic options in metastasized stages. Mesenchymal stem cells (MSC) home to tumours and may therefore serve as a novel therapeutic tool for intratumoral delivery of antineoplastic factors. Tumour necrosis factor (TNF)-relat...
Autores principales: | Luetzkendorf, Jana, Mueller, Lutz P, Mueller, Thomas, Caysa, Henrike, Nerger, Katrin, Schmoll, Hans-Joachim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822570/ https://www.ncbi.nlm.nih.gov/pubmed/19508388 http://dx.doi.org/10.1111/j.1582-4934.2009.00794.x |
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