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Cyclin A2 confers cisplatin resistance to endometrial carcinoma cells via up-regulation of an Akt-binding protein, periplakin
Although overexpression of cyclin A2 is reportedly an indicator of a poor prognosis of various malignancies including endometrial carcinoma, its molecular mechanism remains undetermined. To address this issue, we examined the effect of cyclin A2 on the development of resistance to chemotherapeutic d...
Autores principales: | Suzuki, Akihisa, Horiuchi, Akiko, Ashida, Takashi, Miyamoto, Tsutomu, Kashima, Hiroyasu, Nikaido, Toshio, Konishi, Ikuo, Shiozawa, Tanri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822571/ https://www.ncbi.nlm.nih.gov/pubmed/19583808 http://dx.doi.org/10.1111/j.1582-4934.2009.00839.x |
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