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PARP1 inhibition affects pleural mesothelioma cell viability and uncouples AKT/mTOR axis via SIRT1

Malignant Pleural Mesothelioma (MMe) is a rare but increasingly prevalent, highly aggressive cancer with poor prognosis. The aetiology of MMe is essentially a function of previous exposure to asbestos fibres, which are considered to be an early-stage carcinogen. Asbestos is toxic to human mesothelia...

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Detalles Bibliográficos
Autores principales:	Pinton, Giulia, Manente, Arcangela Gabriella, Murer, Bruno, Marino, Elvira, Mutti, Luciano, Moro, Laura
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2013
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822586/ https://www.ncbi.nlm.nih.gov/pubmed/23301673 http://dx.doi.org/10.1111/jcmm.12000

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