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Cooperative effects of Janus and Aurora kinase inhibition by CEP701 in cells expressing Jak2V617F

The Janus kinase 2 mutant V617F occurs with high frequency in myeloproliferative neoplasms. Further mutations affecting the Janus kinase family have been discovered mostly in leukaemias and in myeloproliferative neoplasms. Owing to their involvement in neoplasia, inflammatory diseases and in the imm...

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Detalles Bibliográficos
Autores principales:	Gäbler, Karoline, Rolvering, Catherine, Kaczor, Jakub, Eulenfeld, René, Méndez, Sergio Álvarez, Berchem, Guy, Palissot, Valérie, Behrmann, Iris, Haan, Claude
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2013
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822589/ https://www.ncbi.nlm.nih.gov/pubmed/23301855 http://dx.doi.org/10.1111/jcmm.12005

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