Bile acids decrease intracellular bilirubin levels in the cholestatic liver: implications for bile acid-mediated oxidative stress

High plasma concentrations of bile acids (BA) and bilirubin are hallmarks of cholestasis. BA are implicated in the pathogenesis of cholestatic liver damage through mechanisms involving oxidative stress, whereas bilirubin is a strong antioxidant. We evaluated the roles of bilirubin and BA on mediatin...

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Detalles Bibliográficos
Autores principales: Muchova, Lucie, Vanova, Katerina, Zelenka, Jaroslav, Lenicek, Martin, Petr, Tomas, Vejrazka, Martin, Sticova, Eva, Vreman, Hendrik Jan, Wong, Ronald James, Vitek, Libor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822628/
https://www.ncbi.nlm.nih.gov/pubmed/20518850
http://dx.doi.org/10.1111/j.1582-4934.2010.01098.x

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