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Analysis of microdissected neurons by (18)O mass spectrometry reveals altered protein expression in Alzheimer's disease
It is evident that the symptoms of Alzheimer's disease (AD) are derived from severe neuronal damage, and especially pyramidal neurons in the hippocampus are affected pathologically. Here, we analysed the proteome of hippocampal neurons, isolated from post-mortem brains by laser capture microdis...
Autores principales: | Hashimoto, Masakazu, Bogdanovic, Nenad, Nakagawa, Hiroyuki, Volkmann, Inga, Aoki, Mikio, Winblad, Bengt, Sakai, Jun, Tjernberg, Lars O |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822682/ https://www.ncbi.nlm.nih.gov/pubmed/21883897 http://dx.doi.org/10.1111/j.1582-4934.2011.01441.x |
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