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Analysis of microdissected neurons by (18)O mass spectrometry reveals altered protein expression in Alzheimer's disease

It is evident that the symptoms of Alzheimer's disease (AD) are derived from severe neuronal damage, and especially pyramidal neurons in the hippocampus are affected pathologically. Here, we analysed the proteome of hippocampal neurons, isolated from post-mortem brains by laser capture microdis...

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Detalles Bibliográficos
Autores principales: Hashimoto, Masakazu, Bogdanovic, Nenad, Nakagawa, Hiroyuki, Volkmann, Inga, Aoki, Mikio, Winblad, Bengt, Sakai, Jun, Tjernberg, Lars O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822682/
https://www.ncbi.nlm.nih.gov/pubmed/21883897
http://dx.doi.org/10.1111/j.1582-4934.2011.01441.x

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