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A novel regulation of VEGF expression by HIF-1α and STAT3 in HDM2 transfected prostate cancer cells

On the basis of increasing roles for HDM2 oncoprotein in cancer growth and progression, we speculated that HDM2 might play a major role in hypoxia-induced metastatic process. For verification of this hypothesis, wild-type LNCaP prostate cancer cells and HDM2 transfected LNCaP-MST (HDM2 stably transf...

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Detalles Bibliográficos
Autores principales: Rathinavelu, Appu, Narasimhan, Madhusudhanan, Muthumani, Praneetha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822688/
https://www.ncbi.nlm.nih.gov/pubmed/22004076
http://dx.doi.org/10.1111/j.1582-4934.2011.01472.x