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Inhibition of JAK2/STAT3 signalling induces colorectal cancer cell apoptosis via mitochondrial pathway

Abnormalities in the JAK2/STAT3 pathway are involved in the pathogenesis of colorectal cancer (CRC), including apoptosis. However, the exact mechanism by which dysregulated JAK2/STAT3 signalling contributes to the apoptosis has not been clarified. To investigate the role of both JAK2 and STAT3 in th...

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Detalles Bibliográficos
Autores principales:	Du, Wan, Hong, Jie, Wang, Ying-Chao, Zhang, Yan-Jie, Wang, Ping, Su, Wen-Yu, Lin, Yan-Wei, Lu, Rong, Zou, Wei-Ping, Xiong, Hua, Fang, Jing-Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2012
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822699/ https://www.ncbi.nlm.nih.gov/pubmed/22050790 http://dx.doi.org/10.1111/j.1582-4934.2011.01483.x

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