Zoledronic acid repolarizes tumour-associated macrophages and inhibits mammary carcinogenesis by targeting the mevalonate pathway

It is unknown whether zoledronic acid (ZA) at clinically relevant doses is active against tumours not located in bone. Mice transgenic for the activated ErbB-2 oncogene were treated with a cumulative number of doses equivalent to that recommended in human beings. A significant increase in tumour-fre...

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Detalles Bibliográficos
Autores principales: Coscia, Marta, Quaglino, Elena, Iezzi, Manuela, Curcio, Claudia, Pantaleoni, Francesca, Riganti, Chiara, Holen, Ingunn, Mönkkönen, Hannu, Boccadoro, Mario, Forni, Guido, Musiani, Piero, Bosia, Amalia, Cavallo, Federica, Massaia, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822730/
https://www.ncbi.nlm.nih.gov/pubmed/19818098
http://dx.doi.org/10.1111/j.1582-4934.2009.00926.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822730/
https://www.ncbi.nlm.nih.gov/pubmed/19818098
http://dx.doi.org/10.1111/j.1582-4934.2009.00926.x

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