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Antigen-Specific T-Cell Activation Independently of the MHC: Chimeric Antigen Receptor-Redirected T Cells

Adoptive T-cell therapy has recently shown promise in initiating a lasting anti-tumor response with spectacular therapeutic success in some cases. Specific T-cell therapy, however, is limited since a number of cancer cells are not recognized by T cells due to various mechanisms including the limited...

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Detalles Bibliográficos
Autores principales:	Chmielewski, Markus, Hombach, Andreas A., Abken, Hinrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822734/ https://www.ncbi.nlm.nih.gov/pubmed/24273543 http://dx.doi.org/10.3389/fimmu.2013.00371

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