Cargando…
Lipophilic but not hydrophilic statins selectively induce cell death in gynaecological cancers expressing high levels of HMGCoA reductase
Recent reports have suggested that statins induce cell death in certain epithelial cancers and that patients taking statins to reduce cholesterol levels possess lower cancer incidence. However, little is known about the mechanisms of action of different statins or the effects of these statins in gyn...
Autores principales: | Kato, S, Smalley, S, Sadarangani, A, Chen-Lin, K, Oliva, B, Brañes, J, Carvajal, J, Gejman, R, Owen, G I, Cuello, M |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822754/ https://www.ncbi.nlm.nih.gov/pubmed/19432822 http://dx.doi.org/10.1111/j.1582-4934.2009.00771.x |
Ejemplares similares
-
Correlation of compliance to statin therapy with lipid profile and serum HMGCoA reductase levels in dyslipidemic patients
por: Grover, Abhinav, et al.
Publicado: (2017) -
Inhibition of HMGCoA reductase by simvastatin protects mice from injurious mechanical ventilation
por: Manitsopoulos, Nikolaos, et al.
Publicado: (2015) -
Functional food mixtures: Inhibition of lipid peroxidation, HMGCoA reductase, and ACAT2 in hypercholesterolemia‐induced rats
por: Mohd Rosmi, Noor Syafiqa Aqila, et al.
Publicado: (2020) -
Combined inhibition of HMGCoA reductase and mitochondrial complex I induces tumor regression of BRAF inhibitor-resistant melanomas
por: de Groot, Evelyn, et al.
Publicado: (2022) -
Synergic effect of Eicosapentaenoic acid and Lovastatin on gene expression of HMGCoA reductase and LDL receptor in cultured HepG2 cells
por: Notarnicola, Maria, et al.
Publicado: (2010)