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Lipophilic but not hydrophilic statins selectively induce cell death in gynaecological cancers expressing high levels of HMGCoA reductase

Recent reports have suggested that statins induce cell death in certain epithelial cancers and that patients taking statins to reduce cholesterol levels possess lower cancer incidence. However, little is known about the mechanisms of action of different statins or the effects of these statins in gyn...

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Detalles Bibliográficos
Autores principales: Kato, S, Smalley, S, Sadarangani, A, Chen-Lin, K, Oliva, B, Brañes, J, Carvajal, J, Gejman, R, Owen, G I, Cuello, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822754/
https://www.ncbi.nlm.nih.gov/pubmed/19432822
http://dx.doi.org/10.1111/j.1582-4934.2009.00771.x

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