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Pathogenesis of colorectal carcinoma and therapeutic implications: the roles of the ubiquitin–proteasome system and Cox-2
Pathways of the molecular pathogenesis of colorectal carcinoma have been extensively studied and molecular lesions during the development of the disease have been revealed. High up in the list of colorectal cancer lesions are APC (adenomatous polyposis coli), K-ras, Smad4 (or DPC4-deleted in pancrea...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Blackwell Publishing Ltd
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822826/ https://www.ncbi.nlm.nih.gov/pubmed/17488476 http://dx.doi.org/10.1111/j.1582-4934.2007.00032.x |