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5′AMP-activated protein kinase α deficiency enhances stress-induced apoptosis in BHK and PC12 cells

5′AMP-activated protein kinase (AMPK) activation occurs under a variety of stress conditions but the role of this enzyme in the promotion or inhibition of stress-induced cell death is unclear. To address this issue, we transformed two different cell lines with shRNA-expressing plasmids, targeting th...

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Detalles Bibliográficos
Autores principales: Shaw, Margaret M, Gurr, Werner K, McCrimmon, Rory J, Schorderet, Daniel F, Sherwin, Robert S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822827/
https://www.ncbi.nlm.nih.gov/pubmed/17488477
http://dx.doi.org/10.1111/j.1582-4934.2007.00023.x