Cargando…

Transcriptional insights on the regenerative mechanics of axotomized neurons in vitro

Axotomized neurons have the innate ability to undergo regenerative sprouting but this is often impeded by the inhibitory central nervous system environment. To gain mechanistic insights into the key molecular determinates that specifically underlie neuronal regeneration at a transcriptomic level, we...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ng, Jian Ming Jeremy, Chen, Minghui Jessica, Leung, Jacqueline YK, Peng, Zhao Feng, Manikandan, Jayapal, Qi, Robert Z, Chuah, Meng Inn, West, Adrian K, Vickers, James C, Lu, Jia, Cheung, Nam Sang, Chung, Roger S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2012
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822849/ https://www.ncbi.nlm.nih.gov/pubmed/21711447 http://dx.doi.org/10.1111/j.1582-4934.2011.01361.x

Ejemplares similares

Ciguatoxin reduces regenerative capacity of axotomized peripheral neurons and delays functional recovery in pre-exposed mice after peripheral nerve injury
por: Au, Ngan Pan Bennett, et al.
Publicado: (2016)

Calcium-activated chloride current expression in axotomized sensory neurons: what for?
por: Boudes, Mathieu, et al.
Publicado: (2012)

Events Occurring in the Axotomized Facial Nucleus
por: Nakajima, Kazuyuki, et al.
Publicado: (2022)

Acute focal brain damage alters mitochondrial dynamics and autophagy in axotomized neurons
por: Cavallucci, V, et al.
Publicado: (2014)

Down-regulation of microglial activity attenuates axotomized nigral dopaminergic neuronal cell loss
por: Song, Dae-Yong, et al.
Publicado: (2013)

Neuronal BDNF Signaling Is Necessary for the Effects of Treadmill Exercise on Synaptic Stripping of Axotomized Motoneurons
por: Krakowiak, Joey, et al.
Publicado: (2015)

Effects of low level laser treatment on the survival of axotomized retinal ganglion cells in adult Hamsters
por: So, Kwok-Fai, et al.
Publicado: (2014)

The role of the cytoskeleton in cell body enlargement, increased nuclear eccentricity and chromatolysis in axotomized spinal motor neurons
por: McIlwain, David L, et al.
Publicado: (2005)

Painful nerve injury increases plasma membrane Ca(2+)-ATPase activity in axotomized sensory neurons
por: Gemes, Geza, et al.
Publicado: (2012)

Activity-dependent degeneration of axotomized neuromuscular synapses in Wld(S) mice
por: Brown, R., et al.
Publicado: (2015)

Comparative Analysis of Retinal Organotypic Cultures and In Vivo Axotomized Retinas
por: González-Riquelme, María José, et al.
Publicado: (2023)

Co-localization of activating transcription factor 3 and phosphorylated c-Jun in axotomized facial motoneurons
por: Park, Byung Gu, et al.
Publicado: (2011)

Impaired nerve fiber regeneration in axotomized peripheral nerves in streptozotocin‐diabetic rats
por: Nishida, Naoki, et al.
Publicado: (2013)

Degeneration of Axotomized Projection Neurons in the Rat dLGN: Temporal Progression of Events and Their Mitigation by a Single Administration of FGF2
por: Hendrickson, Michael L., et al.
Publicado: (2012)

Diffuse axonal injury in brain trauma: insights from alterations in neurofilaments
por: Siedler, Declan G., et al.
Publicado: (2014)

ATG5 overexpression is neuroprotective and attenuates cytoskeletal and vesicle-trafficking alterations in axotomized motoneurons
por: Leiva-Rodríguez, Tatiana, et al.
Publicado: (2018)

Neural Progenitor Cell Implants Modulate Vascular Endothelial Growth Factor and Brain-Derived Neurotrophic Factor Expression in Rat Axotomized Neurons
por: Talaverón, Rocío, et al.
Publicado: (2013)

Microglia and motor neurons during disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis: changes in arginase1 and inducible nitric oxide synthase
por: Lewis, Katherine E, et al.
Publicado: (2014)

Role of Noradrenergic Inputs From Locus Coeruleus on Changes Induced on Axotomized Motoneurons by Physical Exercise
por: Arbat-Plana, Ariadna, et al.
Publicado: (2019)

A Single Intraventricular Injection of VEGF Leads to Long-Term Neurotrophic Effects in Axotomized Motoneurons
por: Calvo, Paula M., et al.
Publicado: (2020)

Microglia Dynamics and Interactions with Motoneurons Axotomized After Nerve Injuries Revealed By Two-Photon Imaging
por: Rotterman, Travis M., et al.
Publicado: (2020)

Thiamine as a peripheral neuro-protective agent in comparison with N-acetyl cysteine in axotomized rats
por: Mousavinezhad-Moghaddam, Maryam, et al.
Publicado: (2023)

Multifaceted role of nitric oxide in an in vitro mouse neuronal injury model: transcriptomic profiling defines the temporal recruitment of death signalling cascades
por: Peng, Zhao Feng, et al.
Publicado: (2012)

Vascular Endothelial Growth Factor (VEGF) Prevents the Downregulation of the Cholinergic Phenotype in Axotomized Motoneurons of the Adult Rat
por: Acosta, Lourdes, et al.
Publicado: (2018)

Water and Ion Channels: Crucial in the Initiation and Progression of Apoptosis in Central Nervous System?
por: Jessica Chen, Minghui, et al.
Publicado: (2008)

Integration of Next-Generation Sequencing Based Multi-Omics Approaches in Toxicogenomics
por: Jayapal, Manikandan
Publicado: (2012)

Connectivity of Pathology: The Olfactory System as a Model for Network-Driven Mechanisms of Alzheimer’s Disease Pathogenesis
por: Franks, Katherine H., et al.
Publicado: (2015)

Regenerative Strategies for Retinal Neurons: Novel Insights in Non-Mammalian Model Organisms
por: Catalani, Elisabetta, et al.
Publicado: (2022)

Impact of gabapentin on neuronal high voltage-activated Ca(2+) channel properties of injured-side axotomized and adjacent uninjured dorsal root ganglions in a rat model of spinal nerve ligation
por: Zhu, Minmin, et al.
Publicado: (2017)

Human Wharton’s jelly mesenchymal stem cells protect axotomized rat retinal ganglion cells via secretion of anti-inflammatory and neurotrophic factors
por: Millán-Rivero, Jose E., et al.
Publicado: (2018)

Removal of the Potassium Chloride Co-Transporter from the Somatodendritic Membrane of Axotomized Motoneurons Is Independent of BDNF/TrkB Signaling But Is Controlled by Neuromuscular Innervation
por: Akhter, Erica Tracey, et al.
Publicado: (2019)

7,8-Dihydroxiflavone Protects Adult Rat Axotomized Retinal Ganglion Cells through MAPK/ERK and PI3K/AKT Activation
por: Galindo-Romero, Caridad, et al.
Publicado: (2021)

Cytokines and olfactory bulb microglia in response to bacterial challenge in the compromised primary olfactory pathway
por: Herbert, Rosalind P, et al.
Publicado: (2012)

Decoding the differential biomarkers of Rheumatoid arthritis and Osteoarthritis: A functional genomics paradigm to design disease specific therapeutics
por: Biswas, Sreyasi, et al.
Publicado: (2011)

Comparative Evaluation of Xerostomia among Diabetic and Nondiabetic Subjects Wearing Complete Denture
por: Sundaram, Manikandan, et al.
Publicado: (2020)

Breaking the HxNy outbreak
por: Manikandan, Jayapal, et al.
Publicado: (2010)

Evaluation of Aromatic Plants and Compounds Used to Fight Multidrug Resistant Infections
por: Perumal Samy, Ramar, et al.
Publicado: (2013)

Editorial: Insights in veterinary regenerative medicine: 2022
por: Roberts, Scott J.
Publicado: (2023)

Regenerative Medicine in Diabetes
por: Matveyenko, Aleksey, et al.
Publicado: (2015)

PKC in Regenerative Therapy: New Insights for Old Targets
por: Rui, Marta, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_2o9801hp523un3iq3dgd5b77ek