Effects of Valproic Acid on Organic Acid Metabolism in Children: A Metabolic Profiling Study

Young children are at increased risk for valproic acid (VPA) hepatotoxicity. Urinary organic acid profiles, as a measure of mitochondrial function, were obtained in children 3.5 to 17.3 years old treated for seizure disorders with valproic acid (VPA; n=52). Age-matched patients treated with carbamaz...

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Detalles Bibliográficos
Autores principales: Price, K.E., Pearce, R.E., Garg, U.C., Heese, B.A., Smith, L.D., Sullivan, J.E., Kennedy, M.J., Bale, J.F., Ward, R.M., Chang, T.K.H., Abbott, Frank S., Leeder, J.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822904/
https://www.ncbi.nlm.nih.gov/pubmed/21544075
http://dx.doi.org/10.1038/clpt.2011.47

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