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Interplay between Ca(2+) cycling and mitochondrial permeability transition pores promotes reperfusion-induced injury of cardiac myocytes
Uncontrolled release of Ca(2+) from the sarcoplasmic reticulum (SR) contributes to the reperfusion-induced cardiomyocyte injury, e.g. hypercontracture and necrosis. To find out the underlying cellular mechanisms of this phenomenon, we investigated whether the opening of mitochondrial permeability tr...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822958/ https://www.ncbi.nlm.nih.gov/pubmed/21199327 http://dx.doi.org/10.1111/j.1582-4934.2010.01249.x |