Mild hypoxia-induced cardiomyocyte hypertrophy via up-regulation of HIF-1α-mediated TRPC signalling

Hypoxia-inducible factor-1 alpha (HIF-1α) is a central transcriptional regulator of hypoxic response. The present study was designed to investigate the role of HIF-1α in mild hypoxia-induced cardiomyocytes hypertrophy and its underlying mechanism. Mild hypoxia (MH, 10% O(2)) caused hypertrophy in cu...

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Detalles Bibliográficos
Autores principales: Chu, Wenfeng, Wan, Lin, Zhao, Dan, Qu, Xuefeng, Cai, Fulai, Huo, Rong, Wang, Ning, Zhu, Jiuxin, Zhang, Chun, Zheng, Fangfang, Cai, Ruijun, Dong, Deli, Lu, Yanjie, Yang, Baofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822973/
https://www.ncbi.nlm.nih.gov/pubmed/22129453
http://dx.doi.org/10.1111/j.1582-4934.2011.01497.x

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