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Activation of the prolyl-hydroxylase oxygen-sensing signal cascade leads to AMPK activation in cardiomyocytes

The proline hydroxylase domain-containing enzymes (PHD) act as cellular oxygen sensors and initiate a hypoxic signal cascade to induce a range of cellular responses to hypoxia especially in the aspect of energy and metabolic homeostasis regulation. AMP-activated protein kinase (AMPK) is recognized a...

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Detalles Bibliográficos
Autores principales:	Yan, Hong, Zhang, Dong-Xia, Shi, Xiaohua, Zhang, Qiong, Huang, Yue-Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2012
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822975/ https://www.ncbi.nlm.nih.gov/pubmed/22128786 http://dx.doi.org/10.1111/j.1582-4934.2011.01500.x

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