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Identification of F-box only protein 7 as a negative regulator of NF-kappaB signalling

The nuclear factor κB (NF-κB) signalling pathway controls important cellular events such as cell proliferation, differentiation, apoptosis and immune responses. Pathway activation occurs rapidly upon TNFα stimulation and is highly dependent on ubiquitination events. Using cytoplasmic to nuclear tran...

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Detalles Bibliográficos
Autores principales: Kuiken, Hendrik J, Egan, David A, Laman, Heike, Bernards, Rene, Beijersbergen, Roderick L, Dirac, Annette M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822984/
https://www.ncbi.nlm.nih.gov/pubmed/22212761
http://dx.doi.org/10.1111/j.1582-4934.2012.01524.x