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The non-anticoagulant heparin-like K5 polysaccharide derivative K5-N,OSepi attenuates myocardial ischaemia/reperfusion injury
Heparin and low molecular weight heparins have been demonstrated to reduce myocardial ischaemia/reperfusion (I/R) injury, although their use is hampered by the risk of haemorrhagic and thrombotic complications. Chemical and enzymatic modifications of K5 polysaccharide have shown the possibility of p...
Autores principales: | Collino, Massimo, Pini, Alessandro, Mastroianni, Rosanna, Benetti, Elisa, Lanzi, Cecilia, Bani, Daniele, Chini, Jacopo, Manoni, Marco, Fantozzi, Roberto, Masini, Emanuela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822989/ https://www.ncbi.nlm.nih.gov/pubmed/22248092 http://dx.doi.org/10.1111/j.1582-4934.2012.01530.x |
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