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Elevated expression of cav-1 in a subset of SSc fibroblasts contributes to constitutive Alk1/Smad1 activation

Previous studies have shown that the transforming growth factor (TGF)β/Alk1/Smad1 signaling pathway is constitutively activated in a subset of systemic sclerosis (SSc) fibroblasts and this pathway is a critical regulator of CCN2 gene expression. Caveolin-1 (cav-1), an integral membrane protein and t...

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Detalles Bibliográficos
Autores principales:	Haines, Paul, Hant, Faye N, Lafyatis, Robert, Trojanowska, Maria, Bujor, Andreea M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2012
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822993/ https://www.ncbi.nlm.nih.gov/pubmed/22277251 http://dx.doi.org/10.1111/j.1582-4934.2012.01537.x

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