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Role of the metastasis-promoting protein osteopontin in the tumour microenvironment

Osteopontin (OPN) is a secreted protein present in bodily fluids and tissues. It is subject to multiple post-translational modifications, including phosphorylation, glycosylation, proteolytic cleavage and crosslinking by transglutamination. Binding of OPN to integrin and CD44 receptors regulates sig...

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Detalles Bibliográficos
Autores principales: Anborgh, Pieter H, Mutrie, Jennifer C, Tuck, Alan B, Chambers, Ann F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822994/
https://www.ncbi.nlm.nih.gov/pubmed/20597997
http://dx.doi.org/10.1111/j.1582-4934.2010.01115.x